He has mentored entrepreneurs and held non-executive directorships of small firms in addition to developing growth programs for SMEs over several years. From 2003 to 2015 he focused on the development of practitioner-led education for entrepreneurship at the University of Cambridge Judge Business School, Centre for Entrepreneurial Learning. His approach has been copied extensively by Institutions.

Dr. Vyakarnam is specialized in board room team development across industries, business growth strategies, mentoring early stage businesses. He is familiar with most industry sectors due to the long experience of working with businesses.

Dr Vyakarnam was awarded "Best Entrepreneurship Professor" at the 2nd Asian Business Schools Awards in 2011. In 2012 he was elected to the prestigious European Academy of Science and Arts.